>Orientation and position >1|P43463|HTH-type transcriptional activator aarP|Providencia stuartii|AraC Chromosomal. >2|P34000|HTH-type transcriptional regulator acrR (Potential acrAB operon repressor)|Escherichia coli O6|TetR AcrR is situated 142 bp downstream and divergently transcribed from the acrAB operon. >8|P33234|HTH-type transcriptional regulator adiY|Escherichia coli|AraC AdiY is located downstream of the biodegradative arginine decarboxylase (adiA) gene. >10|P43464|Transcriptional activator aggR (AAF/I regulatory protein)|Escherichia coli|AraC encoded on the virulence plasmid pAA2. The AAF/I biogenesis genes are organized as two unlinked plasmid-borne regions separated by 9 kb. Region 1 comprises a contiguous cluster of fimbria structural genes, in the order chaperone-usher-putative invasin-pilin genes. AAF/I region 2 encodes AggR. >13|P05052|HTH-type transcriptional regulator appY (M5 polypeptide)|Escherichia coli|AraC The appY gene is located at 13 min on the Eschericha coli chromosome, next to the ompT gene. >25|P17446|HTH-type transcriptional regulator betI|Escherichia coli|TetR The bet region in Escherichia coli comprises four genes, betT, betI, betB and betA, with betT located 128 bp upstream and divergently to the tandemly linked betIBA genes. betIBA genes constitute an operon. >35|P43506|HTH-type transcriptional repressor Bm3R1|Bacillus megaterium|TetR bm3R1 is situated between the genes bm3P1 and P450BM-3. bm3R1 is 304 bp and divergently oriented from bm3P1 and 30 bp upstream with the same orientation that P450BM-3. >37|P26950|F1 operon positive regulatory protein|Yersinia pestis|AraC The caf1R gene is present in the pFra plasmid. >44|Q9ZFU7|HTH-type transcriptional regulator eutR (Ethanolamine operon regulatory protein)|Salmonella typhimurium|AraC EutR is the last gene of the EutR operon and is transcribed in the same direction as the other genes of the operon. >45|P26993|Exoenzyme S synthesis regulatory protein exsA|Pseudomonas aeruginosa|AraC ExsA is in the region known as the exoenzyme S trans regulatory locus that contains three complete open-reading frames and,exsC, exsB and exsA, and a truncated open-reading frame, exsD. >48|P63202|HTH-type transcriptional regulator gadW|Escherichia coli O157:H7|AraC The yhiW gen is in the hdeD-gadA region. >55|P37639|HTH-type transcriptional regulator gadX|Escherichia coli|AraC The yhiXx gene is in the hdeD-gadA region. >61|P31778|Regulatory protein hrpB|Ralstonia solanacearum|AraC Most hrp genes are clustered in a large region on a megaplasmid. >64|P39437|Invasion protein invF|Salmonella typhimurium|AraC InvF is the first open-reading frame of a large cluster of genes that includes at least 12 other genes required for the entry and for encoding the components of the SPI1 type III secretion apparatus. >69|O33813|Lactose operon transcription activator|Staphylococcus xylosus|AraC The lactose utilization lacPH genes are divergent to lacR. >71|Q51872|Probable transcriptional regulator lumQ|Photobacterium leiognathi|AraC The lumQ and lumP genes form the lum operon which is linked to the lux operon, but is transcribed in the opposite direction. The gene order of the lum and lux operon is: transcriptional terminator-lumQ-lumP-regulatory region-luxC-luxD-luxA-luxB-luxN-luxE. The regulatory region includes two promoter systems, the PR-promoter for the lux operon and the PL-promoter for the lum operon. >72|P21308|HTH-type transcriptional regulator luxR|Vibrio harveyi|TetR The genes required for bioluminescence in V. harveyi are in two separate regions, region I and region II. Region I contains the luxCDABE operon, and the region II encodes a regulatory protein, LuxR, which activates transcription of the lux operon. While in V. fischeri luxR and luxI are inmediatly upstream of the genes encoding the enzymes for luminiscence, in Vibrio harveyi there is not regulatory gene upstream of the lux operon. >73|P27246|Multiple antibiotic resistance protein marA|Escherichia coli O157:H7|AraC The chromosomal multiple-antibiotic resistance (mar) locus consists of two divergently transcribed units, marC and marRAB. >75|Q56070|Multiple antibiotic resistance protein marA|Salmonella typhimurium|AraC The Salmonella typhimurium mar locus is structurally and functionally similar to the mar locus of Escherichia coli. >78|P10411|Melibiose operon regulatory protein|Escherichia coli O6|AraC The melR gene is located immediately upstream of the melA gene. The melR gene is transcribed from a single promoter which is divergent from the melAB promoter. >80|P28809|MmsAB operon regulatory protein|Pseudomonas aeruginosa|AraC MmsR is divergent from mmsAB operon. >81|Q00753|Msm operon regulatory protein|Streptococcus mutans|AraC msmR is transcribed divergently from the msm operon genes. >82|P39897|HTH-type transcriptional regulator mtrR|Neisseria gonorrhoeae|TetR The mtrR gene is positioned 250 bp upstream and divergently oriented from the operon mtrCDE. >83|Q04642|Transcriptional regulator mxiE|Shigella flexneri|AraC MxiE is present in invasion plasmid pWR100. >86|Q04642|Transcriptional regulator mxiE|Shigella sonnei|AraC The gene mxiE is in a plasmid. >94|P43459|Transcriptional activator perA|Escherichia coli O127:H6|AraC PerA is encoded by the pMAR2 plasmid, and it is essential for full virulence of enterophatogenic Escherichia coli bacteria. PerA is present in the per region that includes the perA, perB, perC and perD genes, all of which are transcribed in the same direction. >97|Q05587|Regulatory protein pocR|Salmonella typhimurium|AraC PocR gene is located adjacent to and downstream of the pduF gene. The pduF gene encodes a propanediol transporter. Both genes are located in the region between the pdu operon and the cob operon. The pdu and cob operons are transcribed divergently. >100|P23217|HTH-type transcriptional regulator qacR|Staphylococcus aureus subsp. aureus Mu50|TetR The gene qacR is situated 178 bp upstream and divergently transcribed from qacA. >108|P09378|L-rhamnose operon transcriptional activator rhaR|Escherichia coli|AraC RhaS and RhaR are encoded in the same operon (RhaSR). >113|Q9Z3Q6|Transcriptional activator rhrA|Sinorhizobium meliloti|AraC The RhrA gene is in megaplasmid pSymA. >115|P27292|Right origin-binding protein|Escherichia coli O157:H7|AraC Rob is a chromosomal gene. >120|P22539|Regulatory protein soxS|Escherichia coli O157:H7|AraC The SosR and SoxS genes are divergently transcribed. >122|P39885|HTH-type transcriptional regulator tcmR (Tetracenomycin C transcriptional repressor)|Streptomyces glaucescens|TetR The tcmR gene is located 116 bp upstream and divergently transcribed from tcmA. The tcmR and tcmA genes are at the extreme of the tetracenomycin (TCM) operon. This operon contains tcmR, tcmA, as well as the 11 genes implicated in the synthesis of the tetracenomycin C. The tcmP gene is downstream and convergently oriented to tcmA (O-methyltransferase). >124|P03038|Tetracycline repressor protein class A from transposon 1721|Escherichia coli|TetR The gene tetR is situated 39 bp upstream and divergently transcribed from tetA. >126|P04483|Tetracycline repressor protein class B from transposon Tn10|Escherichia coli|TetR The gene tetR is situated 36 bp upstream and divergently transcribed from tetA. >127|P03039|Tetracycline repressor protein class C|Escherichia coli|TetR The gene tetR is situated 7 bp upstream and divergently transcribed from tetA. >128|P09164|Tetracycline repressor protein class D|Escherichia coli|TetR The gene tetR is situated 35 bp upstream and divergently transcribed from tetA. >138|P43462|Probable thc operon regulatory protein|Rhodococcus erythropolis|AraC TchR is transcribed divergently from thcB. >145|P32326|Urease operon transcriptional activator|Escherichia coli|AraC ure R is is transcribed divergently from the ureDABCEFG operon. >146|Q02458|Urease operon transcriptional activator|Proteus mirabilis|AraC ureR is divergently transcribed relative to the genes encoding urease structural and accessory proteins, the first of which is ureD. An intergenic region, consisting of 492 bp of DNA, separates the start codons for ureR and ureD. >151|Q04248|Virulence regulon transcriptional activator virF|Shigella dysenteriae|AraC The VirF gene is present on the large virulence plasmid (Plasmid 210 kb invasion pWR100). >166|P07859|XylDLEGF operon transcriptional activator|Pseudomonas putida|AraC XylS is in the TOL pWW0 plasmid. The promoters of XylS and XylR are divergent. >167|Q04710|XylDLEGF operon transcriptional activator 1|Pseudomonas putida|AraC xylS1 gene is in plasmid TOL pWW53. The XylS1 gene is located downstream of the meta-1 operon and adjacent to the xylR gene. The xylS1 gene is transcribed divergently to xylR. >169|Q05092|XYLDLEGF operon transcriptional activator 2|Pseudomonas putida|AraC The xylS2 gene is present in plasmid TOL pWW53 and is located downstream of the meta-2 operon. >170|Q05335|XYLDLEGF operon transcriptional activator 3|Pseudomonas putida|AraC The XylS3 gene is present in the plasmid TOL pWW53. The gene XylS3 is located between the meta-1 and meta-2 operons. >171|Q04713|XYLDLEGF operon transcriptional activator 1|Pseudomonas putida|AraC The xylS4 gene is located in plasmid TOL pDK1. >172|P55449|Putative HTH-type transcriptional regulator y4fK|Rhizobium sp. NGR234|AraC The y4fK gene is symbiotic plasmid pNGR234a. >180|P77634|Putative HTH-type transcriptional regulator ybcM|Escherichia coli|AraC The ybcm gene is located in the emrE-ruS intergenic region. >195|P76135|HTH-type transcriptional regulator ydeO|Escherichia coli|AraC The ydeO gene is located in the pqqL-hipA region. >200|P77402|Putative HTH-type transcriptional regulator ydiP|Escherichia coli|AraC The ydiP gene is located in the AROD-PPS region. >201|P76241|Putative HTH-type transcriptional regulator yeaM|Escherichia coli|AraC The yeaM gene is located in the gapA-rnD region. >216|P32677|Putative HTH-type transcriptional regulator yijO|Escherichia coli|AraC yijO is in the gldA-ppC region. >217|P40331|Putative HTH-type transcriptional regulator yisR|Bacillus subtilis|AraC yisR is in the wprA-degA region. >222|P77601|Putative HTH-type transcriptional regulator ykgA|Escherichia coli|AraC The ykgA gene is located in the eaeH-betA region. >223|P77379|Putative HTH-type transcriptional regulator ykgD|Escherichia coli|AraC YkgD is located in the eaeH-beta region. >225|P43458|Putative HTH-type transcriptional regulator in mcrB 3'region|Streptomyces lavendulae|AraC YmcR is located in the mcrB 3' region. McrB is involved in mitomycin C-resistance. >227|P77396|Putative HTH-type transcriptional regulator ypdC|Escherichia coli|AraC The ypdC gene is located in the ddg-glk region. >228|Q46855|Putative HTH-type transcriptional regulator yqhC|Escherichia coli|AraC The yghC gene is located in the metC-sufI region. >239|O05142|Operon regulatory protein|Pseudomonas sp.|AraC The regulatory protein encoded by the cbdS gene is in plasmid pBAH1. >242|O05934|Putative regulatory protein (Putative XylS-type protein)|Pseudomonas putida|AraC The potential open reading frame encoding a putative regulatory protein is located upstream of oxoO. >245|O24739|BarB|Streptomyces virginiae|TetR barB is situated 282 bp downstream and with the same orientation as barA. barB is located 161 bp upstream and with the same orientation as varS. >248|O30343|Hemagglutinin/protease regulatory protein|Vibrio cholerae|TetR The hapR gene is located in the chromosome I of Vibrio cholerae (AE003852). The hapR gene is located 305 bp upstream and divergently transcribed from the hpt gene and 211 bp downstream and convergent from the yral gene. >251|O32788|Hypothetical protein ORF17|Lactococcus lactis|AraC This protein is in plasmid pK214. >253|O33453|CymR|Pseudomonas putida|TetR The cymR gene is 844 bp upstream of the cymB gene, the first gene of the cym operon. The cymR and cym operon are located in the chromosome of Pseudomonas putida F1 just upstream of the ctm operon. >255|O51847|Regulatory protein|Pseudomonas putida|AraC It is in the pRE4 plasmid, upstream of the ipbAa gene. Upstream of the ipbR gene is an IS1543 insertion sequence. Between the ipbR gene and the ipbAa gene there are three insertion sequences: IS1544, IS1545 and IS1546. Encompassing the ipb catabolic genes are two identical direct repeats 1007 bp DNA segments. >256|O52558|RifQ|Amycolatopsis mediterranei|TetR The rifQ gene is situated in the rifamycin biosynthetic gene cluster. The gene rifQ is 16 bp from and with the same orientation as the rifP gene. >258|O52834|AlcR (Alcaligin siderophore system regulator)|Bordetella bronchiseptica|AraC AlcR is located downstream of the alcaligin biosynthesis alcABC genes. >259|O52846|XylS/AraC transcriptional regulator|Bacillus megaterium|AraC The bgaR gene is located immediately upstream and divergently transcribed from bgaM. >262|O68276|Putative DNA-binding protein Bm1P1|Bacillus megaterium|TetR bm1P1 is located 266 bp upstream and divergently from the P450BM-1 gene. >263|O68442|Regulatory protein|Agrobacterium tumefaciens|TetR ifeR is 115 bp downstream from ifeB, in the ifeABR operon. >269|O70020|IcaR|Staphylococcus epidermidis|TetR In S. epidermidis, icaR is situated 164 bp upstream and divergently from the ica operon (icaA, icaD, icaB y icaC). >271|O85815|Putative regulatory protein|Pseudomonas sp. IC|AraC It is in the pWW110 plasmid which is a large (circa 210 kb) transmissible catabolic plasmid catabolizing biphenyl/methylbiphenyl. >274|O87252|Positive transcriptional activator|Lactococcus lactis|AraC The orf encoding O87252 is in the bacteriocin-producing pMRC01 plasmid. >278|P72185|Repressor protein|Propionibacterium freudenreichii|TetR The gene hemR is part of the hemYHBXRL gene cluster. The hemR gene is located 50 bp from the hemX gene and divergently oriented. Downstream from hemR, and with the same orientation, is the hemL gene. >282|Q04819|ORF11; NCBI gi: 154251|Salmonella typhimurium|AraC The gene encoding the protein Q04819 was defined as orf11 in the 3' end of rck region and it is located in the 90 kb-plasmid resident in Salmonella typhimurium which confers increased virulence in mice by promoting the spread of the infection after the invasion of the intestinal epithelium. >283|Q07681|Transcriptional activator AfrR|Escherichia coli|AraC AfrR and AfrS are divergent from AfrA. All of these genes can be found in the 132-kb conjugative plasmid of the RDEC-1 strain. This plasmid includes the genes involved in the production of AF/R1 pilus. >291|Q8KLP4|Repressor|Stenotrophomonas maltophilia|TetR The smeT gene is located upstream from the structural operon of the pump genes smeDEF and divergently transcribed from those genes. The smeT gene is 223 bp upstream and divergently oriented from the smeD gene. >296|Q8KNI9|CalR1|Micromonospora echinospora|TetR calR1 is located in the calicheamicin locus from Micromonospora echinospora. The gene calR1 is situated 162 bp upstream and divergently of the gene calU6. The gene calT1 is 70 bp downstram of calR1 and both have the same orientation. >310|Q8KX64|Luminescence regulator LitR|Vibrio fischeri|TetR litR is situated between two ORFs that shared significant (>80%) identity to the hpt (5’ of litR) and lpd (3’ of litR) genes of Vibrio parahaemolyticus. >328|Q8VQC6|VanT|Listonella anguillarum|TetR The gene vanT is situated upstream and convergent from lpd. >335|Q8VVJ2|TetR protein|Corynebacterium glutamicum|TetR Plasmid pTET3. The gene tetR(33) is in the tetracylcine resistance region of pTET3. The tetracylcine resistance region of pTET3 contains two divergently oriented ORFs, ORF21 and ORF22. The gene tetR(33) corresponds to the ORF21, and is situated 39 bp and divergently oriented with respect to ORF22. >350|Q939Q2|JadR*|Streptomyces venezuelae|TetR Streptomyces venezuelae contains two genetic clusters for jadomicyn B biosynthesis. The first is responsible for polyketide biosynthesis and contains the jadR2 and jadR1 regulatory genes. The second is responsible for the biosynthesis of the dideoxysugar component of jadomycin B and contains 12 genes, one of them being jadR*. The cluster jadNXOPQSTUVR*YZ, is 9 kb downstream from the cluster PKS biosynthesis. jadR* is situated 58 bp downstream and convergently from jadV and 45 bp upstream and divergently from jadY genes. >368|Q93M20|Putative transcriptional regulator|Streptomyces aureofaciens|TetR The aur1B gene is located in the aur1 gene cluster. aur1B is situated 175 bp downstream from aur1A and 83 bp upstream from aur1C. The three genes have the same orientation. >377|Q93QZ7|HydR|Clostridium difficile|TetR hydR is on the conjugative transposon Tn5398. hydR is located 344 bp downstream of ilvD and 26 bp upstream of hydD. >383|Q93TU7|Transcriptional repressor|Rhodococcus sp. NCIMB 9784|TetR The campR gene is situated in the gene cluster for the biodegradation of camphor. campR is 177 bp upstream an divergently from the camK gene. >387|Q46985|Regulator of the 4HPA-hydroxylase operon|Escherichia coli|AraC hpaA is transcribed in the same direction as hpaB and hpaC. The hpaA gene is located just upsteam of the hpaBC operon. >388|Q47074|BfpT protein|Escherichia coli|AraC The bfp genes are located in a 1.8 kb fragment of the enteroadherent factor (EAF) plasmid of enteropathogenic Escherichia coli (EPEC). Within this fragment there are three identically-oriented and closely-spaced genes: bfpT, bfpV and bfpW. >393|Q51597|Cam repressor|Pseudomonas putida|TetR The camR gene is adyacent to the P-450cam hydroxylase operon (camDCAB) on the plasmid CAM. The camR gene is 323 bp upstream of the gene camD. Both genes are divergently oriented. >397|Q51995|TmbS|Pseudomonas putida|AraC It is located in the 1,2,4-trimethylbenzene (TMB) catabolic operon: tmbCWURS. >399|Q53603|GapR transcripotional activator|Streptomyces aureofaciens|AraC The gapR gene is adjacent to the structural gene (gap) encoding glyceraldehyde-3-phosphate dehydrogenase. >405|Q56153|JadR2|Streptomyces venezuelae|TetR jadR2 is situated between the jadW3 and jadR1 genes. jadW3 is 80 bp dowstream and convergently of jadR2, and jadR1 is situated 649 bp upstream and divergently from jadR1. >407|Q56790|HrpXv|Xanthomonas campestris pv. vesicatoria|AraC No other hrp gene is located downstream of hrpXv in the same transcription unit. >416|Q60011|Virginiae butanolide receptor|Streptomyces virginiae|TetR The gene barA is between the barX and barB genes. barA is 259 bp upstream and divergently from barX, and 283 bp upstream from and with the same orientation that barB. >840|Q9AIQ9|IcaR|Staphylococcus caprae|TetR Staphyloccus caprae 96007 contains an ica operon whose organization is identical to those of Staphylococcus epidermidis and Staphyloccus aureus ica operons. In S. caprae, icaR is situated 166 bp upstream and divergently from the ica operon (icaA, icaD, icaB y icaC). >841|Q9AIU0|Regulatory protein TtgR|Pseudomonas putida|TetR The ttgR gene is located upstream from tha ttgABC operon and transcribed in opposite direction. The ttgR translation start codon is located 259 bp upstream from the ttgA translation start codon. >842|Q9AJ68|Putative transcriptional repressor ButR|Streptomyces cinnamonensis|TetR butR is 386 bp upstream of ccr, the gene for the crotonyl-CoA reductase. >844|Q9AJL5|VarR|Streptomyces virginiae|TetR The varR gene is located 89 bp upstream of the varS gene that encodes a virginiamycin S specific transporter thaat constitues an operon. >851|Q9AMH9|Putative repressor simReg2 (Sim16)|Streptomyces antibioticus|TetR The simReg2 gene is located within the simocyclinone biosynthetic cluster. The simReg2 gene is located 97 bp upstream and divergently from the simEx1 gene. >862|Q9EVJ6|Repressor protein MphR(A)|Escherichia coli|TetR Plasmid pTZ3509. The mphR(A) gene is the last gene of the mph(A)-mrx-mphR(A) operon. The mphR(A) gene is located immediately downstram of the mxr gene (the initiation codon of mphR(A) overlaps the termination codon of the mrx gene). >866|Q9F0Y2|Pip|Streptomyces coelicolor|TetR pip is situated 38 bp downstream from and transcriptionally coupled with pep. >879|Q9F6W0|CasR|Rhizobium etli|TetR The gene casR is located 166 bp upstream and divergently from the casA gene. >892|Q9F9Z7|PhaD (Fragment)|Pseudomonas resinovorans|TetR phaD is located in the polyhydroxyalkanoate (PHA) synthesis genetic region. phaD is 76 downstream of phaC2 gene, with the same orientation. >893|Q9FA56|Putative regulator (Fragment)|Azoarcus evansii|TetR paaR is the last gene of a sequenced chromosomal region of Azoarcus evansii containing a cluster of 11 phenylacetic acid catabolic (paa) genes (paaYZGHIKABCDE). paaR is located downstream of the paaE gene. >903|Q9KIH5|Putative regulator|Rhizobium etli|TetR rmrR is situated 136 bp upstream and divergently from rmrA, in the rmrAB operon. These genes are in plasmid b. >906|Q9KJC4|ArpR|Pseudomonas putida|TetR arpR is situated upstream and divergently to the arpABC operon. arpR is 248 bp upstream from arpA. >908|Q9KKH9|YsaE|Yersinia enterocolitica|AraC The YsaE gene is included in a chromosomally-encoded type III secretion pathway. >909|Q9KW95|Riorf89 protein|Agrobacterium rhizogenes|AraC The RiORF89 gene is located in a Ri plasmid. >911|Q9KWH8|AdpA homolog (Fragment)|Streptomyces coelicolor A3(2)|AraC The AdpA gene is transcribed in the same direction as the adjacent gene ornA-c which encodes an oligoribonuclease. >918|Q9L6K7|Putative activator protein SefR|Salmonella enteritidis|AraC The sef operon (sefABCD) is located on a small pathogenicity island. SefR is adjacent to sefD and is transcribed divergently to the genes of the sef operon. >921|Q9L7Y6|BenR|Pseudomonas putida|AraC BenR is chromosomally encoded. >923|Q9L8G8|SmcR (VvpR)|Vibrio vulnificus|TetR The scmR coding region is followed by a convergently transcribed homologue of lpd (dihydrolipoamide dehydrogenase). >926|Q9LBV6|BarZ|Streptomyces virginiae|TetR barZ is located in the region downstream of barX. barZ is 34 bp downstream of the orf2 that shows high sequence similarity to so-called pathway-specific transcriptional regulators. >959|Q9R2F3|Xyls/AraC-type transcriptional activator|Acinetobacter sp. NCIMB9871|AraC The gene arrangement is chnB-chnE-chnR. These three genes are transcribed in the same direction. The presence of a putative terminator sequence after the stop codon of chnB suggests that expression of chnE may not be regulated by ChnR. >963|Q9R9T9|Efflux pump regulator SrpR|Pseudomonas putida|TetR srpR forms a gene cluster with srpS. These two genes are upstream of the srpABC operon. srpR is 2 bp downstream from srpS. >965|Q9RA03|Hypothetical repressor protein KstR|Rhodococcus erythropolis|TetR The kstR gene is situated 154 bp upstream of the kstD gene. Both genes are divergently oriented. >966|Q9RAJ1|Inactive regulatory protein|Mycobacterium sp. GP1|TetR In Mycobacterium sp. strain GP1 the gene dhaR is situated 427 bp upstream from and with the same orientation that the dhaA gene. >975|Q9RC93|Orf1 protein|Bacillus sp. GL1|AraC The orf1 is next to the unsatured glucuronyl hydrolase gene. >977|Q9RF00|PhlH|Pseudomonas fluorescens|TetR The gene phlH is situated upstream and divergently from the phlG gene. However, phlH is not related to known phl genes. >978|Q9RF02|PhlF|Pseudomonas fluorescens|TetR The gene phlH is situated upstream and divergently from the phlG gene. However, phlH is not related to known phl genes. >980|Q9RLI7|Hypothetical protein|Pseudomonas aeruginosa|AraC The ORF5 which encodes this protein is located downstream of the czrSRCAB genes involved in Zn and Cd resistance. >983|Q9RPK9|TarA|Streptomyces tendae|TetR tarA is situated 164 bp and divergently from one ORF that shows the best homology with a putative transmembrane efflux protein of Streptomyces coelicolor A3(2). >985|Q9RPV2|HpaA|Salmonella enterica subsp. enterica serovar Dublin|AraC HpaA is in the 4-hydroxyphenylacetate catabolic locus. >986|Q9RR48|Regulatory protein|Azotobacter chroococcum|AraC PobR is adjacent to pobA, the gene for the 4-hydroxybenzoate hydroxylase. >989|Q9S309|Putative AraC-type Regulator|Ruminococcus flavefaciens|AraC It appears to be located in the xylan utilization operon. >998|Q9X421|Xylose regulatory protein|Lactococcus lactis subsp. lactis|AraC The xylR gene is the first one of the xylose metabolism xylRAB operon. >1001|Q9X545|Tetracycline repressor protein TetR|Corynebacterium glutamicum|TetR The gene tetR(Z) is situated 98 bp upstream and divergently transcribed from tetA(Z). >1008|Q9X9I4|Yersiniabactin transcriptional regulator, YbtA|Yersinia enterocolitica|AraC Genes involved in yersiniabactin biosynthesis, transport, and regulation (irp1 to irp9 ybtA, and fyuA) are clustered on the 'core' of the high-pathogenicity island (HPI). >1011|Q9XCC5|Hypothetical transcriptional regulator TylQ|Streptomyces fradiae|TetR tylQ is located 401 pb downstream that the ORF16* that encodes a cytochrome P450 and 341 bp upstream from the tylS regulatory gene. The three genes have the same orientation. >1012|Q9XCC7|Gamma-butyrolactone receptor protein TylP|Streptomyces fradiae|TetR tylP is located in the tylosin biosynthetic (tyl) gene cluster of Streptomyces fradiae. >1014|Q9XDF0|Putative transcriptional repressor|Streptomyces griseus subsp. griseus|TetR nonG is situated in the potential nonactin biosynthesis gene cluster. The gene nonG is situated 89 bp upstream and divergently from the gene nonH. >1015|Q9XDP8|Transcriptional regulator|Acinetobacter calcoaceticus|AraC The AlkR gene is located adjacent to alkM. >1020|Q9Z3Y6|PhbR|Pseudomonas sp. 61-3|AraC phbR can be found upstream from phbB. The phbR gene is transcribed in the opposite direction from the three structural genes phbBAC. >1024|Q9Z601|RegN|Nostoc punctiforme PCC 73102|TetR The gene regN is located in the sequence of 3.7 kb of DNA adjacent to the devR gene. >1033|Q9ZGB7|LanK|Streptomyces cyanogenus|TetR Plamid PSLA2-L. lanK belongs to the landomycin biosynthetic gene cluster (32 genes). lanK is situated 60 bp downstream and convergently from lanGT1 and 190 upstream and divergently from lanJ. >1368|O30507|Arginine regulatory protein (Transcriptional regulator ArgR) (ArgR regulatory protein)|Pseudomonas aeruginosa|AraC argR is in the aot operon, which consists of six genes involved in the transport of arginine and ornithine. The argR gene is the terminal one of the aot operon. ArgR is located upstream of the aruCFGDB operon and it is transcribed in the same direction as the aru genes. >1369|O31249|Transcriptional regulator of XylS /AraC family (XylS/AraC family)|Acinetobacter sp. ADP1|AraC AlkR is located next to alkM, but is in the opposite direction. >1383|O50285|OpaR|Vibrio parahaemolyticus|TetR The gene opaR is locateded 320 bp upstream and divergently transcribed from hpt and 128 bp downstream and convergent from lpd. >1386|O52066|AlcR (Transcriptional regulator)|Bordetella pertussis|AraC AlcR is located downstream of the alcaligin biosynthesis genes alcABC. >1431|O86852|Gamma-butyrolactone binding protein|Streptomyces coelicolor|TetR The gen scbR is located between scba and orfX genes. The scbR gene is 118 bp downstream and divergently oriented with respect to scbA. The distance between the stop codon of scbR and the convergently oriented orfX start codon is 116. >2160|Q53901|ActII protein (Putative transcriptional regulatory protein)|Streptomyces coelicolor|TetR The gene actII-1 is in the actII region flanked by the actinorhodin biosynthesis gene cluster. The gene actII is 111 bp upstream and divergently from the gene actII-2 (SCO5083) that encodes a putative actinorhodin transporter. >2162|Q56951|AraC-like regulator YbtA (Transcriptional regulator YbtA)|Yersinia pestis|AraC The ybtA gene is located upstream of the putative siderophore biosynthetic gene (irp2). >4196|Q9F8V9|TetR family bacterial regulatory protein|Agrobacterium tumefaciens|TetR The ameR gene is 3 bp downstream of the purC gene and 200 bp upstream of the ameA gene. >4308|Q9JN89|Hypothetical protein mmfR (Putative lactone-dependent transcriptional regulator (TetR-family), MmfR)|Streptomyces coelicolor|TetR Plasmid SCP1. mmyf is situated in the methylenomycin biosynthesis gene cluster. The gene mmfR is 195 bp upstream and divergently oriented from the gene mmfL. >4309|Q9JN93|Hypothetical protein mmyR (Putative lactone-dependent transcriptional regulator (TetR-family), MmyR)|Streptomyces coelicolor|TetR Plasmid SCP1. The gene mmyR is located in the methylenomycin biosynthesis gene cluster. The gene mmyR is 151 bp upstream from and with the same orientation that the gen mmfP. >4834|16131152|putative transcriptional regulator|Escherichia coli K12|TetR The gene envR is situated 399 bp upstream and divergently transcribed from acrE. >4926|16077337|transcriptional regulator|Bacillus subtilis subsp. subtilis str. 168|TetR The gene lmrA is situated 40 bp upstream from and with the same orientation that the lmrB gene. Both genes form the lmrAB operon. >5056|15597216|probable transcriptional regulator|Pseudomonas aeruginosa PAO1|TetR The amrR gene is situated 165 bp upstream and divergently from the amrA gene. >5116|15600252|probable transcriptional regulator|Pseudomonas aeruginosa PAO1|TetR PA5059 is homolog to phaD from Pseudomonas syringae. PA5059 is located in the medium-chain-length poly(3-hydroxyalkanoates) (PHA) biosynthesis gene cluster. This cluster is organizated in two consecutives regions: the first contains two synthetase-encoding genes, phaC1 and phaC2, separared by the phaD gene that encodes a depolymerase. Downstream of phaC2 is PA5059. Downstream of PA5059 is the second region with two genes phaF and a homolog to phaI that encode the major PHA granule binding proteins. PA5059 is 56 bp downstream of phaC2 gene, with its same orientation and 44 bp ustream and convergently from phaF gene. >5460|15928251|ica operon transcriptional regulator IcaR|Staphylococcus aureus subsp. aureus N315|TetR In S. aureus, icaR is situated 164 bp upstream and divergently from the ica operon (icaA, icaD, icaB y icaC). >6026|26991683|transcriptional regulator, TetR family|Pseudomonas putida KT2440|TetR PA5006 is homolog to phaD from Pseudomonas oleovorans. PA5006 is located in the medium-chain-length polyhydroxyalkanoates (PHA) biosynthesis genes cluster. This cluster are organizated in two consecutives regions: the first contains two synthetase-encoding genes, phaA and phaC, separared by the gene PP5004 that encodes a depolymerase. Downstream of phaC is PA5006. Downstream of PA5009 is the second region with two genes PP5007 and a PP5008 that encode the major PHA granule associated proteins, GA2 and GA1, homologs to phaF and phaI of Pseudomonas aeruginosa PAO1. PP5006 is 13 bp downstream of phaC gene, with its same orientation and 112 bp ustream and convergently from PP5007 gene. >6853|19552090|transcriptional regulator|Corynebacterium glutamicum ATCC 13032|TetR amtR is situated between two convergently oriented genes, 22 bp downstream and convergently from the yjcc gene (cytrate lyase beta subunit)(Cg10862) and 74 bp apart from the 3'end of the gene in the same orientation which encodes a hypothical protein (Cg10864). >6871|19554126|transcriptional regulator|Corynebacterium glutamicum ATCC 13032|TetR mcbR is situated 183 bp downstream of the Cgl2942 gene (hypothetical membrane protein) and 73 bp convergently of the Cgl2940 gene (Preprotein translocase subunit YidC). >7937|28872258|transcriptional regulator PhaD|Pseudomonas syringae pv. tomato str. DC3000|TetR phaD is located in the medium-chain-length polyhydroxyalkanoates (PHA) biosynthesis genes cluster. This cluster are organizated in two consecutives regions: the first contains a poly(3-hydroxyalkanoate) depolymerase encoding gene, phaB, and phaC that encodes a poly(3-hydroxyalkanoate) polymerase. Downstream of phaC is phaD. Downstream of phaD is the second region with two genes, phaF and phaI, that encode the major PHA granule associated proteins. phaD is 48 bp downstream of phaC gene, with its same orientation and 362 bp ustream and convergently from phaF gene. >9416|O24741|FarA|Streptomyces sp. FRI-5|TetR farA is situated 124 bp downstream of farX. >9417|P13225|Virulence regulon transcriptional activator virF|Yersinia enterocolitica|AraC The virF gene is in the virulence plasmid pYV.