>Comments
>1|P43463|HTH-type transcriptional activator aarP|Providencia stuartii|AraC
AarP is similar to Rob, MarA and SoxS.
>7|P26189|ADA regulatory protein (Regulatory protein of adaptative response) [Contains: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (O-6-methylguanine-DNA alkyltransferase)]|Salmonella typhimurium|AraC
70% similarity to the ada gene of E. coli.
>8|P33234|HTH-type transcriptional regulator adiY|Escherichia coli|AraC
AdiY is similar to EnvY and AppY. An examination of the substitution of AdiY, AppY and EnvY showed that these three proteins could, to some extent, stimulate the other systems.
>13|P05052|HTH-type transcriptional regulator appY (M5 polypeptide)|Escherichia coli|AraC
AppY is mostly similar to CfaD of Escherichia Coli and to VirF of Shigella flexneri.
>14|P11765|Arabinose operon regulatory protein|Citrobacter freundii|AraC
The nucleotide sequence of the araC gene of C. freundii is 83% similar to the araC genes of both E. coli and S. typhimurium, but only 60% similar to that of E. carotovora with respect to the regions they share. The predicted amino acid sequence is highly conserved and shows 96% and 94% similarity to S. typhimurium and E. coli, respectively. E. carotovora shows only a 58% amino acid similarity.
>37|P26950|F1 operon positive regulatory protein|Yersinia pestis|AraC
CafR is similar to AfrR.
>38|P25393|CFA/I fimbrial subunit D (Colonization factor antigen I subunit D)|Escherichia coli|AraC
CfaD is similar to Rns.
>39|P17410|HTH-type transcriptional regulator chbR (Chb operon repressor)|Escherichia coli|AraC
ChbR (CelD) is similar to MelR.
>40|P43460|HTH-type transcriptional activator csvR|Escherichia coli|AraC
CsvR is similar to CfaD (87%).
>45|P26993|Exoenzyme S synthesis regulatory protein exsA|Pseudomonas aeruginosa|AraC
ExsA is similar to LcrF and VirF.
>69|O33813|Lactose operon transcription activator|Staphylococcus xylosus|AraC
In ref 98 is reported that the positive transcriptional regulation of the lacPH genes by LacR in S. xylosus constitutes the first example of a member of the AraC/XylS family regulating lac genes.
>71|Q51872|Probable transcriptional regulator lumQ|Photobacterium leiognathi|AraC
The lumQ gene product shows high similarity to the EnvY and AdiY proteins of E. coli.
>75|Q56070|Multiple antibiotic resistance protein marA|Salmonella typhimurium|AraC
MarA of Salmonella typhimurium is 86% identical to MarA of Escherichia coli.
>81|Q00753|Msm operon regulatory protein|Streptococcus mutans|AraC
MsmR is similar to MelR.
>93|P40883|Regulatory protein pchR|Pseudomonas aeruginosa|AraC
The ability to function both in repression and in activation is unusual in bacterial regulatory proteins. An example is AraC that regulates the expression of genes of arabinose metabolism, whose expression is repressed by AraC, in the absence of arabinose and activates when arabinose is present.
>94|P43459|Transcriptional activator perA|Escherichia coli O127:H6|AraC
PerA is similar to VirF (54%) and is also similar to CfaD and Rns (51%).
>98|Q52620|Regulatory protein pqrA|Proteus vulgaris|AraC
PqrA is similar to SoxS and MarA.
>107|Q48413|Transcriptional activator ramA|Klebsiella pneumoniae|AraC
RamA is weakly related to the E. coli MarA and SoxS proteins.
>109|P40865|L-rhamnose operon transcriptional activator rhaR|Salmonella typhimurium|AraC
This is a conceptual translation. Frameshifts had to be introduced in positions 17 and 34 to produce this ORF. It is a fragment.
>111|P27029|L-rhamnose operon regulatory protein rhaS|Salmonella typhimurium|AraC
It is similar to RhaS in Escherichia coli.
>115|P27292|Right origin-binding protein|Escherichia coli O157:H7|AraC
Rob is similar to SoxS, MarA and TetD.
>121|Q56143|Regulatory protein soxS|Salmonella typhimurium|AraC
SoxS of Salmonella typhimurium is 97% identical to SoxS of Escherichia coli.
>123|P29492|TCP pilus virulence regulatory protein|Vibrio cholerae|AraC
TcpN shows a high degree of homology to the Rns transcriptional activator associated with pilus biosynthesis in enterotoxigenic Escherichia coli, and to VirF, which controls the Yersinia virulence regulon.
>124|P03038|Tetracycline repressor protein class A from transposon 1721|Escherichia coli|TetR
The tet genes of the four clases, A, B, C and D posses analogous modes of transcriptional regulation and their control elements are related.
>126|P04483|Tetracycline repressor protein class B from transposon Tn10|Escherichia coli|TetR
The tet genes of the four clases, A, B, C and D posses analogous modes of transcriptional regulation and their control elements are related.
>127|P03039|Tetracycline repressor protein class C|Escherichia coli|TetR
The tet genes of the four clases, A, B, C and D posses analogous modes of transcriptional regulation and their control elements are related.
>128|P09164|Tetracycline repressor protein class D|Escherichia coli|TetR
The tet genes of the four clases, A, B, C and D posses analogous modes of transcriptional regulation and their control elements are related.
>162|Q06861|Possible virulence-regulating 38 kDa protein|Mycobacterium tuberculosis|AraC
Some similarity to Pseudomonas aeruginosa ornithine utilization regulatory (oruR).
Homology with the VirF protein of Shigella, the VirFy protein of Yersinia and the Cfad, Rns and FapR proteins from various enterotoxigenic Escherichia coli strains.
>170|Q05335|XYLDLEGF operon transcriptional activator 3|Pseudomonas putida|AraC
XylS3 differs in only 5 amino acids with respect to XylS-pWW0.
>171|Q04713|XYLDLEGF operon transcriptional activator 1|Pseudomonas putida|AraC
The 5' end of xylS4 is highly homologous to both xylS1pWW53 and xylSpWW0, whereas its 3' end is identical to xylS3pWW53.
>222|P77601|Putative HTH-type transcriptional regulator ykgA|Escherichia coli|AraC
High similarity to E.coli Rob.
>242|O05934|Putative regulatory protein (Putative XylS-type protein)|Pseudomonas putida|AraC
This putative regulatory protein encoded by oxoS has 32% amino acid identity with ThcR of Rhodococcus sp.
>253|O33453|CymR|Pseudomonas putida|TetR
Pseudomonas putida F1.
>255|O51847|Regulatory protein|Pseudomonas putida|AraC
IpbR has about 56% identity with the XylS regulatory proteins of the TOL plasmid pWWO.
>256|O52558|RifQ|Amycolatopsis mediterranei|TetR
The rifP and rifQ regions shows high sequence similarity and identical gene organization as the operon varS/varR from Streptomyces virginiae.
>258|O52834|AlcR (Alcaligin siderophore system regulator)|Bordetella bronchiseptica|AraC
AlcR shows the highest similarity to PchR of P. aeruginosa and to YbtA of Y. pestis, both of which are involved in siderophore system gene regulation.
>262|O68276|Putative DNA-binding protein Bm1P1|Bacillus megaterium|TetR
Bacillus megaterium ATCC14581.
>263|O68442|Regulatory protein|Agrobacterium tumefaciens|TetR
Agrobacterium tumefaciens 1D1609.
>271|O85815|Putative regulatory protein|Pseudomonas sp. IC|AraC
This putative regulatory protein is similar to the regulatory XylS protein encoded by the Pseudomonas putida pWWO plasmid.
>275|O87613|Hypothetical protein|Pseudomonas aeruginosa|AraC
Orf from which a 44 kDa polypeptide was deduced.
>283|Q07681|Transcriptional activator AfrR|Escherichia coli|AraC
The most closely related proteins are CafR, a regulatory protein associated with the expression of the F1 envelope protein of Yersinia pestis, and Rob, an E. coli regulatory protein.
>291|Q8KLP4|Repressor|Stenotrophomonas maltophilia|TetR
Xanthomonas maltophilia (Pseudomonas maltophilia) (Stenotrophomonas maltophilia) D457R.
>296|Q8KNI9|CalR1|Micromonospora echinospora|TetR
Micromonospora echinospora NRRL 15839.
>347|Q939B1|Tetracycline resistance regulatory protein TetR|Aeromonas salmonicida|TetR
Diferences between the plasmids pRAS3.1 and pRAS3.2 were of minor extend and they are considered as being variants of the same plasmid, pRAS3.
>350|Q939Q2|JadR*|Streptomyces venezuelae|TetR
Streptomyces venezuelae ISP5230.
>389|Q48557|XylS/AraC-type transcription factor (Fragment)|Lactobacillus helveticus|AraC
Incomplete sequence that allows to obtain a translated 87aa peptide.
>394|Q51600|Possible regulator gene (Fragment)|Burkholderia cepacia|AraC
Incomplete sequence that allows to obtain a 53 aa peptide.
>395|Q51695|Hypothetical protein ORF1 (Fragment)|Brevundimonas diminuta|AraC
Incomplete sequence that allows to obtaina a 168 aa peptide.
>397|Q51995|TmbS|Pseudomonas putida|AraC
It is very similar to XylS.
>405|Q56153|JadR2|Streptomyces venezuelae|TetR
Streptomyces venezuelae ISP5230.
Whether tolerance of Streptomyces venezuelae to jadomycin B is mediated by an efflux system as in tetracenomycin C, it is not known since no genes conferring jadomycin B resistance have been identified.
>409|Q56831|Hrp protein (Fragment)|Xanthomonas oryzae|AraC
The complete gene sequence is not available.
>841|Q9AIU0|Regulatory protein TtgR|Pseudomonas putida|TetR
Pseudomonas putida DOT-T1E.
>842|Q9AJ68|Putative transcriptional repressor ButR|Streptomyces cinnamonensis|TetR
Streptomyces cinnamonensis C730.1.
>844|Q9AJL5|VarR|Streptomyces virginiae|TetR
Analysis of the barB-varS operon and the varS-varR operon indicates that the varS gene is transcribed in three different ways: a monocistronic transcript, as a bicistronic barB-varS transcript, and as a bicistronic varS-varR transcript.
>862|Q9EVJ6|Repressor protein MphR(A)|Escherichia coli|TetR
Escherichia coli Tf481A.
>893|Q9FA56|Putative regulator (Fragment)|Azoarcus evansii|TetR
Azoarcus evansii KB740.
>897|Q9K4R5|EbdR protein|Pseudomonas putida|AraC
This protein has been characterized in Pseudomonas putida 01G3, a psychrotrophic strain able to degrade alkylbenzenes at low temperatures.
EbdR is 90% identical to IpbR regulatory protein from P. putida RE204.
>906|Q9KJC4|ArpR|Pseudomonas putida|TetR
Pseudomonas putida S12.
>911|Q9KWH8|AdpA homolog (Fragment)|Streptomyces coelicolor A3(2)|AraC
It is a 117 aa fragment.
>913|Q9KX52|AdpA-like protein (Fragment)|Mycobacterium smegmatis|AraC
It is a 308 aa fragment.
>926|Q9LBV6|BarZ|Streptomyces virginiae|TetR
Streptreptomyces virginiae MAFF 10-06014.
>927|Q9LCD4|HrpX protein (Fragment)|Xanthomonas campestris pv. zinniae|AraC
It is a 113 aa fragment.
>928|Q9LCD5|HrpX protein (Fragment)|Xanthomonas campestris pv. zantedeschiae|AraC
It is a 129 aa fragment.
>930|Q9LCD7|HrpX protein (Fragment)|Xanthomonas campestris pv. vitians|AraC
It is a 129 aa fragment.
>932|Q9LCD9|HrpX protein (Fragment)|Xanthomonas pisi|AraC
It is a 116 aa fragment.
>934|Q9LCE1|HrpX protein (Fragment)|Xanthomonas campestris pv. incanae|AraC
It is a 123 aa fragment.
>935|Q9LCE2|HrpX protein (Fragment)|Xanthomonas campestris pv. carotae|AraC
It is a 113 aa fragment.
>937|Q9LCE4|HrpX protein (Fragment)|Xanthomonas axonopodis pv. alfalfae|AraC
It is a 109 aa fragment.
>938|Q9LCE5|HrpX protein (Fragment)|Xanthomonas axonopodis pv. glycines|AraC
It is a 143 aa fragment.
>963|Q9R9T9|Efflux pump regulator SrpR|Pseudomonas putida|TetR
Pseudomonas putida S12.
>965|Q9RA03|Hypothetical repressor protein KstR|Rhodococcus erythropolis|TetR
Rhodococcus erythropolis SQ1.
>966|Q9RAJ1|Inactive regulatory protein|Mycobacterium sp. GP1|TetR
Mycobacterium sp. GP1.
The presence of a highly conserved dhaA gene in the three phylogenically different organisms Rhodococcus rhodochrous NCIMB13064, Pseudomonas pavonaceae 170, and Mycobacterium sp. GP1, suggest that dhaA has been distributed among these organism by horizontal transfer.
>977|Q9RF00|PhlH|Pseudomonas fluorescens|TetR
Pseudomonas fluorescens CHA0.
>983|Q9RPK9|TarA|Streptomyces tendae|TetR
Streptomyces tendae ATCC31160.
>984|Q9RPT6|AraC-like transcriptional regulator homolog|Streptomyces albus|AraC
From 252 to 321 the polypeptide contains an arginine-rich region.
>990|Q9S311|Putative AraC-type Regulator (Fragment)|Ruminococcus flavefaciens|AraC
It is a 182 aa fragment.
>998|Q9X421|Xylose regulatory protein|Lactococcus lactis subsp. lactis|AraC
In general xylose regulation is negatively regulated in gram-positive organisms but in this case the regulatory mechanism is positive.
The XylR proteins from the majority of gram-positive bacteria fall into the ROK family of transcriptional regulators.
>1005|Q9X950|Hypothetical protein (Fragment)|Streptomyces coelicolor|AraC
It is a 233 aa fragment.
>1006|Q9X959|Multiple antibiotic resistance A protein (MarA) (Fragment)|Salmonella enterica subsp. enterica serovar Dublin|AraC
Incomplete ORF yielding a 71 aminocacid peptide.
>1015|Q9XDP8|Transcriptional regulator|Acinetobacter calcoaceticus|AraC
This protein is similar to AlkR of Acinetobacter sp. ADP1.
>1020|Q9Z3Y6|PhbR|Pseudomonas sp. 61-3|AraC
PbhR has 25´7% identity with OruR of Pseudomonas aeruginosa.
>1024|Q9Z601|RegN|Nostoc punctiforme PCC 73102|TetR
Nostoc punctiforme ATCC29133.
>1026|Q9ZB51|MsmR (Fragment)|Streptococcus pyogenes|AraC
It is a 209 aa fragment.
>1032|Q9ZFW7|Virulence regulating homolog|Pseudomonas alcaligenes|AraC
It is similar to VirS.
>1033|Q9ZGB7|LanK|Streptomyces cyanogenus|TetR
Streptomyces cyanogenus S136.
>1369|O31249|Transcriptional regulator of XylS /AraC family (XylS/AraC family)|Acinetobacter sp. ADP1|AraC
AlkR shares 22% of identical residues with RhaS from Salmonella typhimurium and XylS from the TOL plasmid of Pseudomonas putida.
>1386|O52066|AlcR (Transcriptional regulator)|Bordetella pertussis|AraC
AlcR is similar to PchR of P. aeruginosa and to YbtA of Y. pestis, both of which are involved in siderophore system gene regulation.
>1419|O69703|TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARAC/XYLS-FAMILY) (Transcriptional regulator, AraC family)|Mycobacterium tuberculosis|AraC
This protein has a putative STAS domain in its N-terminal portion. This STAS domain is common in anion transporters of the sulfate transporter family and in antisigma-factor antagonists.
>1443|P73364|AraC subfamily|Synechocystis sp. PCC 6803|AraC
The set of residues comprised between position 4 and 119 aminoacids LumQ is positive for the profile determining a Histidine-receiving module in bacterial sensor systems.
>1452|P95283|PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN|Mycobacterium tuberculosis|AraC
This protein has an arginine-rich low-complexity region located between aa 74 and 122.
>2160|Q53901|ActII protein (Putative transcriptional regulatory protein)|Streptomyces coelicolor|TetR
Streptomyces coelicolor A3(2).
>4196|Q9F8V9|TetR family bacterial regulatory protein|Agrobacterium tumefaciens|TetR
Ame (Agrobacterium multiple efflux).
>4331|Q9K690|Two-component response regulator|Bacillus halodurans|AraC
It is positive for the profile that defines a Histidine-receiving module in bacterial sensor systems (residues 3-119).
>4336|Q9K6P9|Two-component response regulator|Bacillus halodurans|AraC
It is positive for the profile that defines a Histidine-receiving module in bacterial sensor systems (residues 5-122).
>4346|Q9K9C1|Two-component response regulator|Bacillus halodurans|AraC
It is positive for the profile that defines a Histidine-receiving module in bacterial sensor systems (residues 3-120).
>4350|Q9KB26|BH2109 protein|Bacillus halodurans|AraC
It is positive for the profile that defines a Histidine-receiving module in bacterial sensor systems (residues 3-121).
>4353|Q9KBG9|BH1958 protein|Bacillus halodurans|AraC
It is positive for the profile that defines a Histidine-receiving module in bacterial sensor systems (residues 3-120).
>4354|Q9KBL6|Two-component response regulator|Bacillus halodurans|AraC
It is positive for the histidine-receiving module in bacterial sensor systems profile (residues 3-120).
It is positive (borderline) for the Phosphatidylinositol-specific phospholipase X-box domain profile (residues 153-173).
>4360|Q9KDT8|BH1123 protein|Bacillus halodurans|AraC
Between residues 3-120 this protein has a Histidine-receiving module in bacterial sensor systems.
The C-terminal region (residues 506 to 526) is positive (borderline) with a Pas domain profile. Pas domains are involved in numerous signalling proteins where they are used as signal sensor domains. This region is practically included in the region defined by the profile of the XylS/AraC family.
>4453|Q9RIP5|DNA-binding response regulator|Streptococcus pneumoniae|AraC
From residues 3 to 120 is located a Histidine-receiving module typically found in bacterial sensor systems.
>4510|Q9S2C6|Putative regulatory protein|Streptomyces coelicolor|AraC
It is similar to NitR.
>4520|Q9X7Q2|Putative transcriptional regulator|Streptomyces coelicolor|AraC
It has a DNA/RNA helicase domain (DEAD/DEAH box) located between residues 1 and 10.
>4533|Q9XA73|Putative araC-family transcriptional regulator|Streptomyces coelicolor|AraC
It is similar to ArgR.
>4538|Q9Z553|Putative AraC family transcriptional regulator|Streptomyces coelicolor|AraC
From 96 to 207 there is an alanine-rich region.
>4834|16131152|putative transcriptional regulator|Escherichia coli K12|TetR
The acrEF operon was cloned accidentally as envCD genes because AcrEF functionally complemented the crystal violet sensitivity of the envC mutant.
>4926|16077337|transcriptional regulator|Bacillus subtilis subsp. subtilis str. 168|TetR
The organization of the lmrAB operon was identical to those of the emrAB and emrKY operons of Escherichia coli.
>5056|15597216|probable transcriptional regulator|Pseudomonas aeruginosa PAO1|TetR
MexZ is a fragment from AmrR. MexZ lacks the 33 first residues in its N terminus to be identical to AmrR. These 33 amino acids correspond to half of the conserved  DNA  binding domain.
amrA, mexG and mexX are synonyms.
amrB, mexH and mexY are synonyms.
>5116|15600252|probable transcriptional regulator|Pseudomonas aeruginosa PAO1|TetR
PA5059 is homolog to phaD from Pseudomonas syringae, but in Pseudomonas aeruginosa PAO1 phaD is the name of the gene of the PHA depolymerase.
>6026|26991683|transcriptional regulator, TetR family|Pseudomonas putida KT2440|TetR
PA5006 is homolog to phaD from Pseudomonas oleovorans but in Pseudomonas putida KT2440 is the name of the gene PP3280, beta-ketoadipyl CoA thiolase PhaD.
>6853|19552090|transcriptional regulator|Corynebacterium glutamicum ATCC 13032|TetR
Corynebacterium glutamicum ATCC13032.
>9417|P13225|Virulence regulon transcriptional activator virF|Yersinia enterocolitica|AraC
VirF of Yersinia enterocolitica is similar to LcrF of Yersinia pestis.